The Modis Lab Research

Dengue E Type 3 J Virol cover_____________________

Atomic model of dengue virus type 3 based on the crystal structure of the major envelope glycoprotein, E. The packing of E molecules on the viral surface is derived from an electron cryomicroscopy image reconstruction of dengue virus type 2 (Zhang et al., Nat. Struct. Biol. 11, 907-12). Residues on the viral surface that are not conserved in dengue virus type 2 are shown as purple spheres. Residues on the viral surface that are conserved in dengue, yellow fever, tick-borne encephalitis and Japanese encephalitis viruses are shown as orange spheres.

Yorgo Modis, Steven Ogata, David Clements & Stephen C. Harrison (2005). Variable surface epitopes in the crystal structure of dengue virus type 3 envelope glycoprotein. J. Virol., 79, 1223-1231.