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17. J. Wang, A.K.M.A. Satter, C.C. Wang, J.D. Karam, W.H. Konigsberg, T.A. Steitz (1997). Crystal structure of a pol family replication DNA polymerase from bacteriophage RB69. Cell. 89, 1087-1099. PMID: 9215631. (302 Citations).
18. J. Porankiewicz, J. Wang, A.K. Clarke (1998). New insights into the ATP-dependent ClpP protease: E. coli and beyond. Molecular Microbiology, 29, 275-283. PMID: 10320569. (119 Citations)
19. J. Wang*, J.A. Hartling, J.M. Flanagan (1998). Crystal structure determination of Escherichia coli ClpP starting from an EM-derived mask. J. Struct. Biol. 124, 151-163. PMID: 10049803. (30 Citations)
20. L.F. Silvian, J. Wang, T.A. Steitz (1999). Insights into editing from an isoleucyl-tRNA synthetase structure with tRNAile and mupirocin. Science, 285, 1074-1077. PMID: 10446055. (223 Citations).
21. F. Li, J. Wang, T.A. Steitz (2000). Induced dimerization of dimeric Suflobus Shibatae CCA-adding enzyme upon the binding of two tRNAs. J. Mol. Biol. 304, 483-492. PMID: 11090289.
22. C.J. Noren, J. Wang, F.B. Perler (2000). Dissecting the Chemistry of Protein Splicing and its Applications. Angew. Chem. Int. Ed. 39, 450-466. PMID: 10671234. (87 Citations)
23. J. Wang*, J.J. Song, I.S. Seong, M.C. Franklin, S. Kamtekar, S.H. Eom, C.H. Chung (2001). Nucleotide-dependent conformational changes in a protease-associated ATPase HslU. Structure 9, 1107-1116. PMID: 11709174. (103 Citations).
24. J. Wang*, J.J. Song, M.C. Franklin, S. Kamtekar, Y.J. Im, S.H. Rho, I.S. Seong, C.S. Lee, C.H. Chung, S.H. Eom (2001). Crystal structures of the HslVU peptidase-ATPase complex reveal an ATP-dependent proteolysis mechanism. Structure 9, 177-184. PMID: 11250202. (149 Citations).
25. M. Hochstrasser, and J. Wang (2001). Unraveling the means to the end in ATP-dependent proteolysis. Nature Struct. Biol. 8, 294-296. PMID: 11276243.
26. M.C. Franklin, J. Wang, T.A. Steitz (2001). Structure of the replicating complex of a pol alpha family DNA polymerase. Cell 105, 657-667. PMID: 11389835. (310 Citations).
27. J. Wang* (2001). A corrected quaternary arrangement of the peptidase HslV and ATPase HslU in a cocrystal structure. J. Struct. Biol. 134, 15-24. PMID: 11469873.
28. I.S. Seong, M.S. Kang, M.K. Choi, J.W. Lee, O.J. Koh, J. Wang, S. H. Eom, C.H. Chung (2002). The C-terminal tails of HslU ATPase as a molecular switch for activation of HslV peptidase. J. Biol. Chem. 277, 25976-25982. PMID: 12011053. (27 Citations)
29. Y.H. Cheon, H.S. Kim, K.H. Han, A. Abendroth, K. Niefind, D. Schomburg, J. Wang*, Y. Kim (2002). Crystal structure of D-hyantoinase from Bacillus stearothermophilus: insight into stereochemistry of enantioselectivity. Biochemistry, 412, 9410-9417. PMID: 12135362. (57 Citations)
30. F. Li, Y. Xiong, J. Wang, H.D. Cho, K. Tomita, A.M. Weiner, T.A. Steitz (2002). Crystal structure of the Bacillus stearothermophilus CCA-adding enzyme and its complexes with ATP or CTP. Cell 111, 815-824. PMID: 12526808. (45 Citations)
31. J. Wang* (2003). A second response in correcting the HslV-HslU quaternary structure. J. Struct. Biol. 141, 7-8. PMID: 12576015.
32. S. Szep, J. Wang, P. Moore (2003). The crystal structure of a 26-nucleotide RNA containing a hook-turn. RNA, 9, 44-51. PMID: 12554875. (24 Citations)
33. J. Wang*, D.C. Boisvert (2003). Structural basis for GroEL-assisted protein folding from crystal structure of (GroEL-KMgATP)14 at 2.0Åresolution. J. Mol. Biol. 327, 843-855. PMID: 12654267. (52 Citations)
34. J. Wang*, L. Chen (2003). Domain motions in GroEL upon binding of an oligopeptide. J. Mol. Biol. 334, 489-499. PMID: 14623189. (27 Citations)
35. S. Kamtekar, W.D. Kennedy, J. Wang, C. Stathopoulos, D. Soll, T.A. Steitz (2003). The structural basis of cysteine aminoacylation of tRNApro by prolyl-tRNA synthetases. Proc. Natl. Acad. Sci. USA 100, 1673-1678. PMID: 12578991. (20 Citations)
36. Z.S. Juo, G.A. Kassavetis, J. Wang, E.P. Geiduschek, P. B. Sigler. (2003). Crystal structure of a Pol III Transcription Assembly: a yeast Brf1-TBP-DNA ternary complex. Nature 422, 534-539. PMID: 12660736. (36 Citations)
37. J. Yoon, B. Oh, K. Kim, J.E. Park, J. Wang, H.K. Kim, Y. Kim (2003). Modifying the oligomeric state of cyclic amidase and its effect on enzymatic catalysis. Biochem. Biophys. Res. Commun. 310, 651-659. PMID: 14521961.
38. Y. Xiong, F. Li, J. Wang, A.M. Weiner, T.A. Steitz (2003). Crystal structure of an archaeal class I CCA-adding enzyme and its nucleotide complexes. Mol. Cell 12, 1165-1172. PMID: 14636575. (43 Citations)
39. C.X. Wang, E. Zakharova, J. Li, C.M. Joyce, J. Wang, W. Konigsberg (2004). Pre-steady-state kinetics of RB69 DNA polymerase and its exo domain mutants: effect of pH and thiphosphoryl linkages on the 3'-5' exonuclease activity. Biochemistry 43, 3853-3861. PMID: 15049692.
40. E. Zakharova, J. Wang, W. Konigsberg. (2004). The activity of selected RB69 DNA polymerase mutants can be restored by manganese ions: the existence of alternative metal ion ligands used during the polymerase cycle. Biochemistry 43, 6587-6595. PMID: 15157091.
41. H.J. Merianos, J. Wang, P.B. Moore (2004). The structure of a ribosomal S8/spc operon mRNA complex. RNA 10, 954-964. PMID: 15146079. (25 Citations)
42. P.L. Adams, M.R. Stahley, A.B. Kosek, J. Wang*, S.A. Strobel* (2004). Crystal structure of a self-splicing group I intron with both exons. Nature 430, 45-50. PMID: 15175762. (226 Citations).
43. J. Wang* (2004). Nucleotide-dependent domain motions with rings of the RecA/AAA+ superfamily. J. Struct. Biol. 148, 259-267. PMID: 15522774. (32 Citations)
44. R. Pattanayek, J. Wang, T. Mori, Y. Xu., C.H. Johnson, M. Egli (2004). Visualizing a circadian clock protein: crystal structure of KaiC and functional insights. Mol. Cell 15, 375-388. PMID: 15304218. (50 Citations)
45. S. Kamtekar, A.J. Berman, J. Wang, J.M. Lazaro, M. deVega, L. Blanco, M. Salas, T.A. Steitz (2004). Insights into strand displacement and processivity from the crystal structure of the protein-primed DNA polymerase of bacteriophage phi29. Mol. Cell 16, 609-618. PMID: 15546620. (48 Citations)
46. P.L. Adams, M.R. Stahley, M.L. Gill, A.B. Kosek, J. Wang, S.A. Strobel (2004). Crystal structure of a group I intron splicing intermediate. RNA 10, 1867-1887. PMID: 15547134. (56 Citations)
47. S.A. Strobel, P.L. Adams, M.R. Stahley, J. Wang (2004). RNA kink turns to the left and to the right. RNA 10, 1852-1854. PMID: 15547133. (22 Citations)
48. J. Wang*, S. Kamtaker, A.J. Berman, T.A. Steitz (2005). Correction of X-ray intensities from single crystals containing lattice-translocation defects. Acta Cryst. D61, 67-74. PMID: 15608377.
49. G. Yang, J. Wang, W. Konigsberg (2005). Base selectivity is impaired by mutants that perturb hydrogen bonding networks in the RB69 DNA polymerase active site. Biochemistry 44, 3338-3346. PMID: 15736944. (20 Citations)
50. J. Wang* (2005). Recent cyanobacterial Kai protein structures suggest a rotary clock. Structure 13, 735-741. PMID: 15893664.
51. J. Wang*, S.H. Rho, H.H. Park, S.H. Eom (2005). Correction of X-ray intensities from an HslV-HslU co-crystal containing lattice-translocation defects. Acta Cryst. D61, 932-941. PMID: 15983416.
52. I. Rodriguez, J. Lazaro, L. Blanco, S. Kamtekar, A. Berman, J. Wang, T.A. Steitz, M. Salas, M. deVega, (2005) A specific subdomain of 29 DNA polymerase confers both processivity and strand displacement capacity. Proc. Natl. Acad. Sci. USA 102, 6407-6412. PMID: 15845765.
53. E. Park, Y.M. Rho, O. Koh, S.W. Ahn, I.S. Seong, J.J. Song, O. Bang, J.H. Seol, J. Wang, S.H. Eom, C.H. Chung, (2005) Role of the GYVG pore moitif of HslU ATPase in protein unfolding and translocation for degradation by HslV peptidase. J. Biol. Chem. 280, 25976-25982. PMID: 15849200. (44 Citations)
54. J. Wang*, S. Gulich, C. Bradford, M. Ramirez-Alvarado, L. Regan, (2005). A twisted four-sheeted model for an amyloid fibril. Structure 13, 1279-1288. PMID: 16154085. (23 Citations)
55. J. Wang*, (2005). Hoogsteen Base-Pairing in DNA replication. Nature 437, E6-E7. PMID: 16163299.
56. M.A. Talavera. E.E. Matthews, W.K. Eliason, I. Sagi, J. Wang, A. Henn, E.M. De La Cruz, (2006). Hydrodynamic Characterization of the DEAD-box RNA Helicase DbpA. J. Mol. Biol. 355, 697-707. PMID: 16325852.
57. H. Zhang, C. Rhee, A. Bebenek, J.W. Drake, J. Wang, W. Konigsberg, (2006). The L561A substitution in the nascent base-pair binding pocket of RB69 DNA polymerase reduces base discrimination. Biochemistry 45, 2211-2220. PMID: 16475809.
58. S. Kamtekar, A.J. Berman, J. Wang, J.M. Lazaro, M. de Vega, L. Blanco, M. Salas, T.A. Steitz (2006). The phi29 DNA polymerase:protein-primer structure suggests a model for the initiation to elongation transition. EMBO J. 25, 1335-1343. PMID: 16511564. (26 Citations)
59. M.R. Stahley, P.L. Adams, J. Wang, S.A. Strobel. (2007). Structural metals in the Group I intron: A ribozyme with a multiple metal ion core. J. Mol. Biol. 372, 89-102. PMID: 17612557.
60. S.H. Rho, H.H. Park, G.B. Kang, Y.J. Im, M.S. Kang, B.K., Lim, I.S. Seong, J. Seol, C.H. Chung, J. Wang, S.H. Eom (2008). Crystal structure of Bacillus subtilis CodW, a noncanonical HslV-like peptidase with an impaired catalytic apparatus. Proteins 71, 1020-1026. PMID: 17979190.
61. G. Yang, J. Wang, Y. Cheng, G.E. Dutschman, H. Tanaka, M. Baba, Y.C. Cheng (2008). Mechanism of inhibition of human immunodeficiency virus type 1 reverse transcriptase by a stavudine analogue, 4'-ethynyl stavudine triphosphate. Antimicrob. Agents Chemother. 52, 2035-2042. PMID: 18391035.
62. M.F. Calabrese, C.M. Eakin, J.M. Wang, A. D. Miranker (2008). A regulatable switch mediates self-association in an immunoglobulin fold. Nature Struct. & Mol. Biol. 15, 965-971. PMID: 19172750. (30 Citations)
63. S. Hare, P. Cherepanov, J. Wang* (2009). Application of general formulas for the correction of a lattice-translocation defect in crystals of a lentiviral integrase in complex with LEDGF. Acta Cryst. D65, 966-973. PMID: 19690374.
64. S. Hare, F. Di Nunzio, A. Labeja, J. Wang, A. Engelman, P. Cherepanov. (2009). Structural basis for functional tetramerization of lentiviral integrase. PLoS Pathogens 5, e1000515. PMID: 19609359. (22 Citations)
65. H. Zhang, J. Beckman, J. Wang, W. Konigsberg (2009). RB69 DNA polymerase mutants with expanded nascent base-pair-binding pockets are highly efficient but have reduced base selectivity. Biochemistry 48, 6940-6950. PMID: 19522539.
66. G.M. Clayton, S.G. Aller, J. Wang, V. Unger, J.H. Morais-Cabral. (2009). Combining electron crystallography and X-ray crystallography to study the MlotiK1 cyclic nucleotide-regulated potassium channel. J. Struct. Biol. 167, 220-226. PMID: 19545635.
67. H. Sharma, S. Yu, J. Kong, J. Wang, T. A. Steitz. (2009). Structure of apo-CAP reveals that large conformational changes are necessary for DNA binding. Proc. Natl. Acad. Sci. USA 206, 16604-16609. PMID: 19805344.
68. G. Yang, E. Paintsil, G.E. Dutschman, S.P. Grill, C.J. Wang, J. Wang, H. Tanaka, T. Hamasaki, M. Baba, Y.C. Cheng. (2009). Impact of novel HIV-1 reverse transcriptase mutations P119S and T165A on 4'-ethynylthymidine analog resistance profile. Antimicrob. Agents Chemother. 52, 2035-2042. PMID: 19704131.
69. K.D. Smith, S.V. Lipchock, T.D. Ames, J. Wang, R.R. Breaker, S.A. Strobel (2009) Structural basis of ligand binding by a c-di-GMP riboswitch. Nature Struct. Mol. Biol. 16, 1218-1223. PMID: 19898477. (44 Citations)
70. N. Toor, K., Keating, O. Fedorova, K. Rajashankar, J. Wang*, A.M. Pyle* (2010) Tertiary Architecture of the Oceanobacillus Iheyensis Group II intron. RNA 16, 57-69. PMID: 19952115.
71. A.L. Cortajarena, J. Wang, & L. Regan (2010). Crystal structure of a designed tetratricopeptide repeat module with its peptide ligand. FEBS J. 277, 1058-1066. PMID: 20089039.
72. R.J. Tomko, Jr., M. Funakoshi, K. Schmeider, J. Wang, & M. Hochstrasser (2010). Heterohexameric ring arrangement of the eukaryotic proteasomal ATPases: implications for proteasome structure and assembly. Mol. Cell 38, 393-403. PMID: 20471945. (27 Citations)
73. J. Beckman, M. Wang, G. Blaha, J. Wang*, & W.H. Konigsberg* (2010). Substitution of Ala for Tyr567 in RB69 DNA polymerase allows dAMP to be inserted opposite 7,8-dihydro-8-oxoguanine. Biochemistry 49, 4116-4125. PMID: 20411947.
74. J. Beckman, M. Wang, G. Blaha, J. Wang*, & W.H. Konigsberg* (2010). Substitution of Ala for Tyr567 in RB69 DNA polymerase allows dAMP and dGMP to be inserted opposite guanidinohydantoin. Biochemistry. 49, 8554-8563. PMID: 20795733.
75. J. Wang* (2010). Inclusion of weak high-resolution X-ray data for improvement of a group II intron structure. Acta Cryst. D66, 988-1000. PMID: 20823550.
76. H. Yang*, J. Wang*, X. Jia, M. W. McNatt, T. Zhang, B. Pan, H. W. Wang, P. D. Bieniasz, & Y. Xiong (2010). Structural insight into the mechanisms of enveloped virus tethering by tetherin. Proc. Natl. Acad. Sci. USA 107, 18428-18432. PMID: 20940320.
77. R. M. Mitton-Fry, S. J. Degregorio, J. Wang, T. A. Steitz, & J. A. Steitz (2010). Poly(A) tail recognition by a viral RNA element through assembly of a triple helix. Science 330, 1244-1247. PMID: 21109672.
78. M. Wang, S. Xia, G. Blaha, T. A. Steitz, W. H. Konigsberg, & J. Wang (2011). Insights into base selectivity from the 1.8 Åresolution structure of an RB69 DNA polymerase ternary complex. Biochemistry 50, 581-590. PMID: 21158418.
79. S. Xia, M. Wang, H. R. Lee, A. Shiha, G. Blaha, T. Christian, J. Wang, & W. Konigsberg. (2011). Variations in mutation rates caused by RB69pol fidelity mutants can be rationalized on the basis of their kinetic behavior and crystal structures. J. Mol. Biol. 406, 558-570. PMID: 21216248.
80. E. B. Butler, Y. Xiong, J. Wang, & S. A. Strobel (2011). Structural basis of cooperative ligand binding by the glycine riboswitch. Chem. Biol. 18, 293-298. PMID: 21439473.
81. S. Xia, W. H. Konigsberg, & J. Wang (2011). Hydrogen-bonding capability of a templating difluorotoluene nucleotide residue in an RB69 DNA polymerase ternary complex. J. Am. Chem. Soc. 133, 10003-10005. PMID: 21667997.
82. S. Xia, M. Wang, G. Blah, W. H. Konigsberg, & J. Wang (2011) Structural insights into complete metal ion coordination from ternary complexes of B family RB69 DNA polymerase. Biochemistry 50, 9114-9124. PMID: 21923197.
83. S. Xia, S. H. Eom, W. H. Konigsberg, & J. Wang (2012) Structural basis for differential insertion kinetics of dNMPs opposite a difluorotoluene nucleotide residue. Biochemistry. 51, 1476-1485. PMID: 22304682.
84. S. Xia, S. H. Eom, W. H. Konigsberg, & J. Wang (2012) Bidendate and tridendate metal-ion coordination within the ternary complex of RB69 DNA polymerase. Proteins Sci. 21, 447-451. PMID: 22238207.