Publications:

22.     Stanley, B.J., Ehrlich, E.S., Short, L., Yu, Y., Xiao, Z., Yu, XF & Xiong, Y. (2008). Structural Insight into the HIV Vif SOCS Box and Its Role in Human E3 Ubiquitin Ligase Assembly. J Virol. [Epub ahead of print]

21.     Xiong, Y. (2008). From electron microscopy to X-ray crystallography: molecular replacement case studies. Acta Cryst. D64, 76-82.

20.     Lomakin, I.B.*, Xiong, Y.*# & Steitz, T.A.# (2007). The crystal structure of yeast fatty acid synthase, a cellular machine with eight active sites working together. Cell 129, 319-332. (*: equal contributions; #: corresponding authors).

19.     Xiong, Y. & Steitz, T.A. (2006). A story with a good ending: tRNA 3'-end maturation by CCA-adding enzymes. Curr Opin Struct Biol. 16, 12-17.

18.     Li, W., Kamtekar, S., Xiong, Y. , Grindley, N.D. & Steitz, T.A. (2005). Structure of a synaptic resolvase tetramer covalently linked to two cleaved DNAs. Science 309, 1210-1215.

17.     Xiong, Y. & Steitz, T.A. (2004). Mechanism of transfer RNA maturation by CCA-adding enzyme without using an oligonucleotide template. Nature 430, 640-645.

16.     Xiong, Y. , Li, F., Wang, J., Weiner A.M. & Steitz, T.A. (2003). Crystal Structures of an Archaeal Class I CCA-Adding Enzyme and Its Nucleotide Complexes. Molecular Cell 12, 1165-1172.

15.     Pan, B., Xiong, Y. , Shi, K. & Sundaralingam, M. (2003). Crystal structure of a bulged RNA tetraplex at 1.1 Å resolution: Implications for a novel binding site in RNA tetraplexe. Structure 11, 1423-1430.

14.     Pan, B., Xiong, Y. , Shi, K. Deng, J. & Sundaralingam, M. (2003). Crystal structure of an RNA purine-rich tetraplex containing adenine tetrads: Implications for specific binding in RNA tetraplexes. Structure 11, 815-823.

13.     Pan, B., Xiong, Y. , Shi, K. & Sundaralingam, M. (2003). An eight-stranded helical fragment in RNA crystal structure: Implications for tetraplex interaction. Structure 11, 825-831.

12.     Deng, J., Xiong, Y. , Pan, B. & Sundaralingam, M. (2003). Structure of an RNA dodecamer containing a fragment from SRP domain IV of E. coli. Acta Cryst. D59, 1004-1011.

11.     Main, E., Xiong, Y. , Cocco, M., D'andrea, L. & Regan, L. (2003). Design of Stable a Helical Arrays from an Idealized TPR Motif. Structure 11, 497-508.

10.     Li, F., Xiong, Y. , Wang, J., Cho, H., Tomita, K., Weiner, A.M. & Steitz, T.A. (2002). Crystal structures of Bacillus Stearothermophilus CCA-adding enzyme and its complexes with ATP or CTP. Cell 111, 814-824.

9.     Smansy, S.M., Xiong, Y. , Hemann C., Hille R., Sundaralingam, M. & Cowan, J. (2002). Crystal Structure and Stability Studies of C77S HiPIP: A Serine Ligated [4Fe-4S] Cluster. Biochemistry 41, 1195-1201.

8.     Deng, J.*, Xiong, Y.* & Sundaralingam, M. (2001). X-ray analysis of an RNA tetraplex (UGGGGU)4 with divalent Sr2+ ions at subatomic resolution (0.61 Å). Proc. Natl. Acad. Sci. USA. 98,13665-13670. (*: equal contributions).

7.     Xiong, Y. , Deng, J., Sudarsanakumar, C. & Sundaralingam, M. (2001) Crystal Structure of an RNA Duplex r(gugucgcac) with Uridine Bulges. J. Mol. Biol. 313, 573-82.

6.     Deng, J., Xiong, Y. , Sudarsanakumar, C., Shi, K. & Sundaralingam, M. (2001). Crystal structures of two forms of a 14-mer RNA/DNA chimer duplex with double UU bulges: a novel intramolecular U*(A-U) base triple. RNA 7, 1425-31.

5.     Xiong, Y. & Sundaralingam, M. (2001). Protein-nucleic acid interaction: major groove recognition determinants. In Encyclopedia of Life Sciences (Macmlllan Reference Ltd, London). URL: http://www.mrw.interscience.wiley.com/emrw/9780470015902/els/article/a0003138/current/pdf

4.     Xiong, Y. & Sundaralingam, M. (2000). Two Crystal Forms of helix II of the X. Laevis 5S rRNA with a cytosine bulge. RNA 6, 1316-1324.

3.     Xiong, Y. & Sundaralingam, M. (2000). Crystal structure of a DNAoRNA hybrid duplex with a polypurine RNA r(gaagaagag) and a complementary poly pyrimidine DNA d(CTCTTCTTC). Nucleic Acids Res. 28, 2171-2176.

2.     Sudarsanakumar, C., Xiong, Y. , & Sundaralingam, M. (2000). Crystal structure of an adenine bulge in the RNA chain of a DNA-RNA hybrid, d(TTCCTCTTC)-(gaagagagag). J. Mol. Biol. 299, 103-112.

1.     Xiong, Y. & Sundaralingam, M. (1998). Crystal structure and conformation of a DNA·RNA hybrid duplex with a polypurine RNA strand: d(TTCTTBr5CTTC)-(gaagaagaa). Structure 6, 1493-1501.