CHI is a set of commands for performing global computational searching of protein helix interactions. The methods used by CHI have been developed as a result of the modelling of the transmembrane helices of glycophorin A and phospholamban.

Features of CHI version 1.1:

• Commands can be run from any directory
• Enhanced error checking
• Automatic helix building from sequence
• Web-based input file generation
• Web-based input file editing
• User control over scope of the search
• Choice of molecular dynamics algorithms
• Parallel execution for CPU intensive jobs
• Experimental distance restraints
• Automatic generation of input for Xmgr plotting program
• HTML documentation

Problems should be reported to PaulAdams at Yale University.