SHARP is a computer program for macromolecular crystallography. It operates on reduced, merged and scaled data from SIR(AS), MIR(AS) and MAD experiments, refines the heavy-atom model, helps detect minor or disordered sites using likelihood-based residual maps, and calculates phase probability distributions for all reflexions in the dataset.

To use SHARP please ask Shanti Kunchaparty to create a user account for you (available for CSB users only). SHARP runs from within a browser (here netscape) and requires that over 2MB of SHARP environment files be deposited in your working directory.  To access the SHARP environment you will need a special user ID and password.

Once you have obtained these just type (from a CSB computer):

setup sharp

To see what this is all about, CSB core members (only) may browse the manual and tutorials.

Note: CSB core members and sharp administrators may access the CSB SHARP server from outside the CSB private network by clicking here.